The automaker says spiders may build webs in a vent hose and cause the fuel tank to crack and lead to an increased risk of a fire.
The recall affects 2010 to 2012 Mazda-6 vehicles equipped with 2.5 liter engines.
Mazda says it will notify owners and dealers will fix the problem at no charge.
This is the second time in three years Mazda has issued a recall because of spiders.
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