According to MoDOT, traffic on the interstate was rerouted to U.S. Highway 69 due a non-hazardous spill this morning.
The accident closed both directions of I-35.
Northbound traffic had to be rerouted onto U.S. Highway 69 at Exit 68 north of Winston.
MoDOT rerouted southbound traffic at Exit 78 near Pattonsburg.
One northbound has since reopened along with all southbound lanes of I-35.
Officials said it could take more than two hours to clear the spill and reopen all lanes of traffic.