Troopers responded to 263 accidents over the four day counting period.
Troopers also arrested 142 people for driving while intoxicated.
One of the fatal accidents claimed the life of a northwest Missouri man.
The Highway Patrol said 39-year-old Andrew Mathews of Plattsburg died when he was thrown off his ATV after it went off the side of the road.
Troopers said Mathews was not wearing a helmet.
The accident happened on Route Y in Plattsburg on Thursday.