The new location will be the eighth for Dot Transportation Inc., a subsidiary of Dot Foods.
Dot chose St. Joseph, partially because of its location between the company's headquarters in Mt. Sterling, Ill., and Colorado.
DTI recruiters are currently looking for 10 experienced drivers throughout the region to jump start the new location.
The company is working with the St. Joseph Chamber of Commerce to scout potential locations. Property owners are encouraged to contact Sarah Wolfe with DTI, at 1-800-366-3687.