The pending forecast is calling for rain, freezing rain, ice and some snow across the state over the next few days.
According to the patrol, snow and ice last week resulted in 10 traffic fatalities in a 24-hour period.
The patrol encourages drivers to eliminate non-essential travel and to postpone any driving until crews have had time to treat roads. If driving is essential, they suggest planning ahead and driving safely.
Motorists can call ahead to check road conditions by calling 1-888-275-6636. MoDOT also has road condition maps available online and through their mobile app.
If you are involved in an accident or need emergency assistance, call the patrol's emergency number at 1-800-525-5555 or dial *55 from cell phones.