The explosion happened about an hour east of Kansas City, just outside of Houstonia at 11:55 P.M. Thursday night.
People from over thirty miles away have reported seeing the explosion light up the sky, while reports of housing shaking came from as far away as Sedalia.
A spokesperson from Panhandle Eastern says the pipeline valve was shut off and the flames were contained by 2:30 A.M.
According to Pettis County Sheriff Kevin Bond, crews were still battling fires at several buildings near the explosion after the pipeline was contained.
Emergency crews have reported evacuations following the explosion, but no injuries have been reported.
The cause of the blast is still under investigation.
Stay with KQ2 throughout the day for more on this breaking news story as it develops.